As its name clears that they may be fever specific and it is true they are. But the truth of their action is not limited only to the fevers of different kinds but they are more extensive in action on nerves as well as on the liver and spleen, Dr.N.L.Sinha has observed keenly the actions of these remedies and concluded that “Their action on the motor nerves of the blood vessels that keeps functioning the organs of the circulation of the blood including heart, arteries and veins. Cerebellum, the plexes solaris, the sympathetic nerves and ganglion also comes under its influence” And new research proves that these remedies are acting on such nervous diseases with better prognosis and the said remedies again stands with honest that they are even nerve specific as many congenital nervous disorders also got recovered with these remedies. They are the drug of choice in the exalted or depressed state of the diseased nerves and thus becomes the chief remedies for the nervous constitution, as all we agree that because of nervousness the organs mostly heart, stomach, liver, intestines gets affected after a long time, and the fundamental cause is found in lifestyle or trait that either got genetically or after effects of surroundings. And no doubt Febrifugo becomes here chief constitutional remedy, and modern days life style is call for it, and intellectual and a logical practitioner who takes all minutes of case history surely takes benefit of using it in a proper case with hundred percent success that is an art, must be learnt in Electro-Homeopathy practice. Being as fever specific is mostly used in tropical, intermittent fevers, typhus, malaria, and even the chronic fevers of idiopathic origin also comes under the influence of these remedies. As its some peculiarities resembles with S10 so it can be used in number of cases of gastro intestinal diseases and as well as bilious disorders according to the desired effects in positive or negative doses that is either by stimulating the Liver, Gall bladder, Stomach, Intestines or getting exact opposite action by opposite dilutions. It can be added with different Electricities but Yellow electricity also possesses somewhat similar action of F2 and can be used successfully in number of cases.